Abstract

This methods paper describes how mathematical models for predicting the epidemiological and health economic effects of vaccination should be performed to be presented to STIKO. This methods paper shall be routinely reviewed and updated as necessary. The target audience of this methods paper is the professional community.

This methods paper was developed within a research project funded by the Federal Ministry of Health (BMG) (www.rki.de/steering). It aims to make a further contribution to the standardization of the STIKO workflow, the quality of vaccination recommendations in Germany, and the transparency of the decision making processes. This methods paper will describe the EM approach of predicting epidemiological effects and HEs. The manner in which analyses of certain vaccinations should be designed depends, among other things, on the respective research question and the scientific evidence available. For that reason, its presentation is project-specific.

EMs and HEs commissioned by STIKO or the RKI are primarily intended to support the STIKO in developing the most efficient vaccination strategy. However, the results of EMs and HEs are only one aspect upon which the STIKO bases its decisions.

  • Functioning
  • Europe
  • Germany